Reactome cholesterol biosynthesis

Author: nsyt

August undefined, 2024

WebSep 4, 2024 · GseaPreranked function in Gene Set Enrichment Analysis (GSEA) (version 2.2.2, Broad Institute, Cambridge, MA, USA) was performed using the Reactome cholesterol synthesis signature (Additional file 5: Table S4), downloaded from the Molecular Signature Database (MsigDB, version 6.0, Broad Institute). WebNov 3, 2015 · The REACTOME_CHOLESTEROL_BIOSYNTHESIS and HORTON_SREBF_TARGETS gene sets were manually curated from the …

Impact of Statins on Gene Expression in Human Lung Tissues

WebJan 17, 2024 · pathway Summary Regulation of cholesterol biosynthesis by SREBP (SREBF) Cite Download Contents 1 Identity 2 Interactions 3 Chemicals 4 Proteins 5 Genes 6 … WebREACTOME_CHOLESTEROL_BIOSYNTHESIS Human Gene Set: REACTOME_CHOLESTEROL_BIOSYNTHESIS For the Mouse gene set with the same name, see REACTOME_CHOLESTEROL_BIOSYNTHESIS See MSigDB license terms here porsche carbon floor mats

Cholesterol biosynthesis II (via 24,25-dihydrolanosterol)

WebMay 5, 2024 · Cholesterol biosynthesis is upregulated in the destruxin-resistant sublines As overexpression of ABC drug efflux transporters did not account for destruxin resistance, cross-resistance of all three sublines to various chemotherapeutic drugs as well as other fungal metabolites was investigated. WebFeb 25, 2024 · Genes belonging to the molecular signature database gene sets “glycolysis” (n = 29) and “cholesterol biosynthesis” (n = 24) were identified as glycolytic and … WebNov 4, 2015 · Statins are 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors that alter the synthesis of cholesterol. Some studies have shown a significant association of statins with improved respiratory health outcomes of patients with asthma, chronic obstructive pulmonary disease and lung cancer. porsche car cake

Necrotic debris and STING exert therapeutically relevant effects …

WebDec 7, 2024 · The gene sets REACTOME_GLYCOLYSIS and REACTOME_CHOLESTEROL_BIOSYNTHESIS were obtained from the Molecular Signatures Database (MsigDB) database ( http://www.gsea-msigdb.org/gsea/index.jsp ). A gene set variation analysis (GSVA) and differential expression analysis were executed using the … porsche car clubs near meWebRegulation of cholesterol biosynthesis by SREBP (SREBF) Sterol regulatory element binding proteins (SREBPs, SREBFs) respond to low cholesterol concentrations by transiting to … porsche car covers for sale

"WebJan 4, 2024 · The top 10 DAMP-induced transcripts, based on 3D-cultured cell responses ( Fig S2C ), revealed a cholesterol acetyltransferase gene (SOAT), implicated in converting cholesterol to less toxic cholesterol esters, to be highly induced in 3D but not in 2D cultures. " - Reactome cholesterol biosynthesis

Reactome cholesterol biosynthesis

6.1: Cholesterol synthesis - Medicine LibreTexts

WebBiological pathway information for Bloch pathway from Reactome. Webreactome_hs_gag_biosynthesis reactome_hs_gag_degradation reactome_hsf1_activation reactome_hsf1_dependent_transactiva tion reactome_hsp90_chaperone_cycle_for_ …

Did you know?

WebREACTOME_CHOLESTEROL_BIOSYNTHESIS Human Gene Set: REACTOME_CHOLESTEROL_BIOSYNTHESIS For the Mouse gene set with the same … WebReactome is pathway database which provides intuitive bioinformatics tools for the visualisation, interpretation and analysis of pathway knowledge. Reactome 4,4-dimethylcholesta-8(9),24-dien-3beta-ol is oxidized to 4 …

WebThe transformation of zymosterol into cholesterol can follow either of routes, one in which reduction of the double bond in the isooctyl side chain is the final step (cholesterol … WebJan 17, 2024 · Regulation of cholesterol biosynthesis by SREBP (SREBF) This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped …

WebOct 4, 2016 · Cholesterol is an essential component of cell membranes and the precursor for the synthesis of steroid hormones and bile acids. The synthesis of this molecule … WebRefSeq Summary (NM_005063): This gene encodes an enzyme involved in fatty acid biosynthesis, primarily the synthesis of oleic acid. The protein belongs to the fatty acid desaturase family and is an integral membrane protein located in the endoplasmic reticulum. Transcripts of approximately 3.9 and 5.2 kb, differing only by alternative ...

WebView Gene Families for REACTOME_CHOLESTEROL_BIOSYNTHESIS. The following table provides a functional overview of the MSigDB gene sets by categorizing their genes into a …

WebFeb 1, 2024 · The results showed that salidroside significantly reduced cholesterols, esterified cholesterols, fatty acids, unsaturated fatty acids and triacylclycerols biosynthesis in liver through down-regulating the genes expressions of sterol regulatory element-binding proteins ( Srebf1 and Srebf2 ). sharp wiktionaryWebMar 3, 2024 · Furthermore, microarray analysis indicated that these three PFASs, at a concentration of 100 μM, downregulated genes involved in cholesterol biosynthesis. The data also pointed to, among others, changes in cellular processes, such as PERK/ATF4 signaling, tRNA aminoacylation and expression of amino acid transporters by PFOA, PFOS … porsche car brandWeb29 rows · REACTOME_CHOLESTEROL_BIOSYNTHESIS: Systematic name: M16227: Brief … sharp window tint burleson txWebDec 7, 2024 · Glycolysis and cholesterol synthesis related gene sets were obtained from the Molecular Signatures Database to perform the gene set variations analysis. The … sharp wifeWebSep 20, 2024 · Reactome * 603414 TRANSMEMBRANE 7 SUPERFAMILY, MEMBER 2; TM7SF2 Alternative titles; symbols. ANG1 HGNC Approved Gene Symbol: TM7SF2. Cytogenetic location: ... (300205), a narrow range of enzymes within the cholesterol biosynthesis pathway. Subsequent accumulation of the 8,9-unsaturated sterol substrates … sharpwin instagramWebBiological pathway information for Cholesterol biosynthesis II (via 24,25-dihydrolanosterol) from Plant Reactome. sharpwin heals instagramWebHuman Gene Set: KEGG_FATTY_ACID_METABOLISM. Standard name. KEGG_FATTY_ACID_METABOLISM. Systematic name. M699. Brief description. Fatty acid metabolism. Full description or abstract. Collection. sharp win11